Advances on The Novel Drug Deliver System:Bacterial Ghost
- VernacularTitle:细菌菌蜕作为新颖药物递送体系的研究进展
- Author:
Ruiping ZHANG
;
Zhaoshan ZHANG
- Publication Type:Journal Article
- Keywords:
bacterial, bacterial ghost, vaccine, delivery system
- From:
Progress in Biochemistry and Biophysics
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Bacterial ghost is intact bacterial envelope which is lysised by the lysis geneE of PhiX174. It can be used as vaccine directly. Foreign antigen can be targeted into outer membrane, inner membrane or the periplasmic space of bacterial, as a result, a recombinant bacterial ghost is constructed. Bacterial ghost, as a novel drug delivery system, is becoming more and more concerned, which can deliver DNA and protein vaccine or other drugs in order to have a better immune responses and therapeutic effects.
