The prediction of neonatal respiratory distress syndrome by stable microbubble test and surfactant protein A level in gastric aspirate
- VernacularTitle:胃液稳定微泡试验及表面活性蛋白A检测对新生儿呼吸窘迫综合征预测的意义
- Author:
Yue XIN
;
Rongxiu ZHENG
;
Jing WANG
;
Guilan CHU
- Publication Type:Journal Article
- Keywords:
Respiratory distress syndrome, newborn;
Gastric aspirate;
Surfactant protein A
- From:
Chinese Journal of Laboratory Medicine
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the application of stable microbubble test ( SMT) and surfactant protein A ( SP-A) level in gastric aspirate in predicting neonatal respiratory distress syndrome ( RDS). Methods One hundred and ten high-risk preterm infants within 1 hour after birth, with gestational age between 24 and 36 weeks, birth weight between 1 160 g and 2 010 g were admitted in the study. The gastric secretion of 1-2 ml was collected during routine aspiration for SMT. At the same time SP-A level was measured by enzyme linked immuno sorbent assay. Results The SMT count and SP-A level in preterm infants with RDS were lower than those of infants without RDS [SMT: (5. 7?2. 4) microbubbleg/mm2( mb/ mm2) vs. (12.4?6.0) mb/mm2, t = 8. 355,P