Advance in The Studies on Histone Methylation
- VernacularTitle:组蛋白甲基化研究进展
- Author:
Xiaoqing TIAN
;
Jingyuan FANG
- Publication Type:Journal Article
- Keywords:
histone methylation, histone methyltransferase, histone demethylase, gene expression regulation
- From:
Progress in Biochemistry and Biophysics
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Histone methylation is one of the epigenetic modifications. Histone methylation influences constitutive heterochromatin, genomic imprinting, inactivation of X-chromosome and gene transcription regulation. Abnormality of histone methylation is associated with several carcinomas. The discovery of enzymes that reverse histone methylation challenges the current understanding that histone methylation is a stable epigenetic marker and provides a novel way to study histone modifications.
