Nervous system relapse in primary plasma cell leukemia
- VernacularTitle:罕见的原发性浆细胞白血病神经系统复发
- Author:
Jie LIN
;
Daobin ZHOU
;
Ying XU
;
Bing HAN
;
Jun FENG
;
Yuandong SHAN
;
Ruie FENG
- Publication Type:Journal Article
- Keywords:
primary plasma cell leukemia;
nervous system replapse
- From:
Basic & Clinical Medicine
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To improve the anderstanding of clinical profile of primary plasma cell leukemia.Methods Case report and literature review.Results A rare case of nervous system relapse in primary plasma cell leukemia was reported.Six patients were identified from the literature.The type of immunoglobulin included IgG(3 patients),IgD(2 patients).Clinical manifestations of nervous system were variable.The average interval from initial diagnosis to the development of nervous system relapse was 16.5 months.Plasma cells were found in cerebrospinal fluid in 4 patients.The mean surviaval time was 6.7 months after nervous system relapse.Conlusion Nervous system relapse in primary plasma cell leukemia is rare with poor prognosis.
