Analysis of the relationship between the coronary plaque morphology and tumor necrosis factor-alpha,endothelin and Interleukin-6 of peripheral circulation hematoplasma
- VernacularTitle:冠状动脉斑块形态与外周血肿瘤坏死因子、内皮素和白细胞介素-6的关系
- Author:
Yongchun ZHANG
;
Luli HUANG
;
Tingye LOU
- Publication Type:Journal Article
- Keywords:
Coronary heart disease;
Tumor necrosis factor-alpha;
Endothelin;
Interleukin-6
- From:
Chinese Journal of Interventional Cardiology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between tumor necrosis factor-alpha(TNF-?), endothelin(ET) and Interleukin-6(IL-6) plasma level of coronary heart disease(CHD) patients and the type of the coronary plaque morphology.Methods Peripheral blood samples were taken from 230 CAG confirmed CHD patients and the same number of CAG normal patients.Serum TNF-?,ET and IL-6 values were measured through enzyme-labeled immunosorbent assay(ELISA) technique in the 2 groups and their relationship between coronary plaque morphology were assesed.Results The mean levels of serum TNF-?,ET and IL-6 in the CHD group were higher than those of the normal group(P