Antibiotic Pretreatment and Bacterial Colonization in Respiratory Tract in Liver Transplanted Patients
- VernacularTitle:抗菌药物的预防应用与肝移植患者气道内细菌的定植
- Author:
Yingmin MA
;
Qing SONG
;
Feihu ZHOU
;
Liang PAN
;
Fei XIE
- Publication Type:Journal Article
- Keywords:
Antibiotic;
Intensive care unit;
Nosocomial infection
- From:
Chinese Journal of Nosocomiology
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the epidemiological conditions of bacterial colonization in respiratory tract,and antibiotic resistance under the antibiotic pretreatment in liver transplanted patients. METHODS From Oct 2002 to Jan 2005,121 liver transplanted patients were admitted to ICU.Among them,45 patients who were intubated more than 48 hours were included in this study.All of the patients received antibiotic pretreatment after operation.Sputum specimens were collected after 24 hours and 48 hours in ICU via the intubated tube with bronchoscopy. RESULTS Thirty nine pathogens were isolated from 36 patients during 48 hours.Pseudomonas aeruginosa was the predominant pathogen.Only 8 bacilli were susceptible to the antibiotics. CONCLUSIONS Although antibiotic pretreatment performed,bacterial colonization in respiratory tract emerges early in liver transplanted intubated patients.Antibiotic pretreatment may make the susceptible bacteria escape.
