Effect of enzymes-hydrolyzed wheat bran on antioxidant ability in diabetes rats
- VernacularTitle:麦麸酶解产物对糖尿病大鼠抗氧化能力的影响
- Author:
Xia JIAO
- Publication Type:Journal Article
- Keywords:
enzymes-hydrolyzed wheat bran;
diabetes mellitus/drug therapy;
antioxidants
- From:
Journal of Jilin University(Medicine Edition)
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of enzymes-hydrolyzed wheat bran(EHWB) on antioxidant system in diabetic rats.Methods Diabetes mellitus models were induced by alloxan injection and EHWB was used to test its effect on anti-oxidative capacity;the EHWB was given intragastrically(i.g.),sodium ferulate(SF) as a positive group.The level of blood glucose,total anti-oxidative capacity(T-AOC),the activities of superoxide dismutase(SOD),glutathione peroxidase(GSH-Px),and xanthine oxidase(XOD),and the content of malondiadehyde(MDA) were detected respectively in serum and liver of rats.Results EHWB significantly decreased the level of blood glucose and increased the level of T-AOC,as well as the activities of GSH-Px and SOD,and decreased the activity of XOD and the content of MDA.However,there was no difference between the groups feeding SF and EHWB.Conclusion EHWB can be used to decrease blood glucose and improve antioxidant ability in diabetes mellitus rats,the effect of EHWB is similar to SF.The effect of decreasing blood glucose of EHWB is related to protecting liver.
