Expression of cyclooxygenase-2 in gastric carcinoma and its relationship with patho-parameters
- VernacularTitle:环氧合酶-2在胃癌组织中的表达及与病理参数的关系
- Author:
Junhua LEI
;
Yang WANG
;
Shaohui CHENG
- Publication Type:Journal Article
- Keywords:
gastric neeplasms;
cyclooxygenase-2;
immunohistochemistry
- From:
Journal of Jilin University(Medicine Edition)
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of of cyclooxygenase-2(COX-2) in human gastric carcinoma and to identify the significance of COX2 expression. Methods COX-2 protein expressions were deteced in 12 nomal gastric mucosa and 40 gastric carcinoma tissues by immunohistochemistry.Results The expression of COX-2 in gastric carcinoma tissues(87.5%) was significantly higher than that in normal gastric mucosa(25.0%)(P