Changes in serum VEGF-C and VEGF-A levels and VEGF-C expression in tissue in patients with gastric carcinoma
- VernacularTitle:胃癌患者血清VEGF-C和VEGF-A的水平变化及VEGF-C在胃癌组织中的表达
- Author:
Jinwei ZHAO
;
Guangyi WANG
- Publication Type:Journal Article
- Keywords:
gastric neoplasms;
endothelial growth factors;
lymphyatic metastasis
- From:
Journal of Jilin University(Medicine Edition)
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the significance of serum VEGF-A and VEGF-C levels in relation to conventional clinopathological parameters of gastric carcinoma,investigate the relationship between serum VEGF-C level and expression of VEGF-C in carcinoma tissue.Methods 28 patients with gastric carcinoma and 21 healthy controls were included in the current study.Serum VEGF-C and VEGF-A levels were assessed by enzymed-linked immunosorbent assay(ELISA).The expression of VEGF-C protein in gastric carcinoma tissue from 28 patients who underwent curative gastrectomy was examined by immunohistochemistry.Results Serum VEGF-C and VEGF-A levels were higher in patients with gastric carcinoma than those in the healthy controls(P
