Study on manufacture of indomethacine Pellet LR by method of strengthening gradually
- Author:
-- -- Emwuthy
- Publication Type:Journal Article
- Keywords:
indomethacine Pellet LR, manufacture
- MeSH:
Indomethacin;
Pharmaceutical Preparations;
Capsules
- From:Pharmaceutical Journal
2004;44(6):21-23
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The goal: Pellet was introduced into sustained release product containing indometacin to promote the advantage of this drug form. The material: Indometacin (China), avicel pH 101 (Taiwan), lactose (Holland), polyvinylpyrolidon (Holland), hydroxypropyl methylcellulose (England)… The method: Pellet indometacin was prepared by layering method. The result: the optimal formulary to prepare sustained release pellet indometacin using layering method was selected. Coated pellet may be filled into the capsules shell or compressed into tablet having sustained release effect by oral (up to 12h)
