Drug-resistant Gene and Disinfectant-resistant Gene for MRSA
- VernacularTitle:耐甲氧西林金黄色葡萄球菌耐药基因及耐消毒剂基因的研究
- Author:
Zhidong HU
;
Jin LI
;
Rui MA
;
Hairu XU
;
Bin TIAN
;
Bin ZHOU
;
Na YUE
- Publication Type:Journal Article
- Keywords:
Meticillin-resistant Staphylococcus aureus(MRSA);
drug-resistant gene;
Disinfectant;
Disinfectant-(resistant) gene
- From:
Chinese Journal of Nosocomiology
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study the drug resistance,drug-resistant genes and(disinfectant)-resistant genes of(MRS)A.METHODS The drug resistance and mecA gene of the ?-lactamase and aac(6′)/aph(2″),aph(3′)-Ⅲ,ant(4′,4″) genes of aminoglycoside and qac(A/B) disinfectant-resistant genes were(detected) in 47 strains of MRSA.(RESULTS) In all 47 strains of MRSA,46 MRSA isolates were mecA positive,39 MRSA isolates were aac(6′)/aph(2″) positive,30 MRSA isolates were aph(3′)-Ⅲ positive,6 MRSA isolates were ant(4′,4″) positive,and 19 MRSA isolates were qac(A/B) positive.CONCLUSIONS MRSA is multiple-drug resistant.The main resistant mechanisms of MRSA to aminoglycosides and disinfectant are related to the drug-resistant genes of aminoglycoside and disinfectant-resistant genes.Clinic physician must pay attention to the diagnosis and(therapy) of MRSA,and control the hospital infection.
