Delayed hypoxic preconditioning decreases the level of cPKC? protein expression in cerebral cortex of mice
- VernacularTitle:延迟性低氧预适应降低小鼠脑皮质cPKC?蛋白表达
- Author:
Song HAN
;
Chenchen NIU
;
Junfa LI
- Publication Type:Journal Article
- Keywords:
cerebral hypoxic preconditioning;
conventional protein kinase C;
membrane translocation;
protein expression;
brain
- From:
Basic & Clinical Medicine
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the role of conventional protein kinase C(cPKCs) in delayed hypoxic preconditioning.Methods The biochemistry techniques of SDS-PAGE,Western bolt and Gel Doc imagine were applied to analyze the effect of repetitive hypoxic exposure(H5,H6) on the level of cPKC?,? membrane translocation and protein expression in murine brain.Results We found that cPKC? protein expression was significantly decreased(P
