Comparisons of curative effects from interventional therapy,palliative operation,and palliative operation combined with 125I seed implantation for advanced pancreatic carcinoma
- VernacularTitle:放射介入、姑息手术以及姑息手术联合~(125)I粒子植入治疗晚期胰腺癌临床疗效比较
- Author:
Xin LI
;
Dianrong XIU
;
Junjie WANG
- Publication Type:Journal Article
- Keywords:
Advanced pancreatic carcinoma;
Palliative operation;
~(125)I seed implantation
- From:
Chinese Journal of Minimally Invasive Surgery
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate curative effects of interventional therapy,palliative operation,and palliative operation combined with ~(125)I seed implantation for the treatment of advanced pancreatic carcinoma.Methods A total of 103 patients with unresectable pancreatic cancer were treated with percutaneous transhepatic cholangiography and drainage(Interventional Group,15 patients),or cholangiojejunostomy and gastroenterostomy(Palliative Group,60 patients),or palliative operation combined with ultrasound-guided ~(125)I seed interstitial implantation(Combination Group, 28 patients),respectively.Results Of 21 patients with preoperative pain in the Combination Group,the rate of partial pain relief and complete pain relief were 14.3%(3/21) and 76.2%(16/21),respectively,which were significantly higher than those in the other two groups(?~2=6.305,P=0.012;?~2=4.525,P=0.033).The median survival time was significantly longer in the Combination Group(8 months) than in the Palliative Group(7 months) and the Interventional Group(2 months)(P=0.0005).Conclusions Percutaneous transhepatic cholangiography and drainage can be applied to patients who cannot tolerate open surgery.Conventional palliative operations combined with ~(125)I seed implantation benefits the patients both in survival time and in pain relief.
