Antimicrobial Susceptibility and Molecular Epidemiology of Imipenem-Resistant Pseudomonas aeruginosa
- VernacularTitle:耐亚胺培南铜绿假单胞菌的耐药性及分子流行病学研究
- Author:
Rui CHEN
;
Yingchun TANG
;
Jiaxin ZHU
;
Jianguo LI
;
Xiangmin PENG
- Publication Type:Journal Article
- Keywords:
Pseudomonas aeruginosa;
Imipenem;
Resistance;
Molecular epidemiology
- From:
Chinese Journal of Nosocomiology
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study the antimicrobial susceptibility and molecular epidemiology of imipenem-resistant Pseudomonas aeruginosa isolated from patients in burn wards in a hospital of Guangzhou. METHODS A total of 48 imipenem-resistant isolates were collected,antimicrobial susceptibility was tested by KirbyBauer disk diffusion method.Random amplified polymorphic DNA(RAPD) typing was carried out to analyze the homology. RESULTS All isolates were multiresistant,the orders of sensitivity rates of antibiotics were CIP,TOB,AMK,GEN,and FEP.Forty eight strains were classified into types A,B,C,and D based on RAPD pattern,types A and B were the most epidemic clones. CONCLUSIONS The prevalence of imipenemresistant P.aeruginosa in burn wards of the hospital is due to nosocomial infection.The prevalent strains are multiresistant.
