Expression of Ki-67 antigen and Survivin gene is enhanced and inter-ralated in epithelial ovarian tumors
- VernacularTitle:Ki-67抗原和Survivin基因在上皮性卵巢癌中表达增强且相关
- Author:
Aifang SHEN
;
Xingsheng YANG
;
Bing CHEN
;
Qingsong MA
- Publication Type:Journal Article
- Keywords:
Ki-67;
Survivin;
epithelial ovarian tumors
- From:
Basic & Clinical Medicine
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of Ki-67 antigen and Survivin in epithelial ovarian tumor and their relationship.Methods Immunohistochemical assay SP method)was used to examine the expression of Ki-67 antigen and Survivin in 24 cases of benign and 47 cases of malignant epithelial ovarian tumor.Results The staining reaction of Ki-67 was mainly confined to the cellular nucleus.Ki-67 index in malignant tumor(19.59?16.48) was significantly higher than that in benign epithelial ovarian tumor(0.17?0.20)(P