Effect of Ixeris sonchifoila on inner ear function of guinea pig after noise exposure
- VernacularTitle:苦碟子注射液对豚鼠噪声暴露后内耳功能恢复的影响
- Author:
Yan ZHANG
;
Bo DU
;
Baodong DU
- Publication Type:Journal Article
- Keywords:
hearing impaired persons;
compositae;
threshold shift;
cochlea;
hair cells;
audiometry,evoked response
- From:
Journal of Jilin University(Medicine Edition)
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Ixeris sonchifoila,a kind of Chinese traditional medicine on noise-induced hearing loss.Methods Fourty-two guinea pigs were divided into two groups.The animals were exposed under 110 dB(n=21) and 120 dB(n=21) noise,separately.Each group was divided into medicine group(n=7),saline group(n=7) and control group(n=7).Ixeris sonchifoila was used in the medicine group and saline in the saline group immediately after the noise exposure by abdomen injection.The threshold was recorded 7 and 14 d later by ABR.Cochlea patch was performed to find hair cell loss.Results By using Ixeris sonchifoila,the threshold shift was significantly reduced(P
