Experimental model of post-operative intra-peritoneal adhesion in rats
- VernacularTitle:术后病理性腹腔粘连大鼠模型制作的实验研究
- Author:
Li ZENG
;
Lijun LING
;
Guoshou XIA
;
Haiyan CHEN
;
Li QIAN
;
Weiping CHEN
- Publication Type:Journal Article
- Keywords:
Abdominal cavity's adhesion;
Rat;
Model;
File
- From:
Journal of Medical Postgraduates
2003;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To set up an animal model of intraabdominal adhesion after surgery. Methods:A new rat model of intraabdominal adhesion was made by using pincers,dry gauze,hemostatic clamps and razor blade.Rat appendix was used to produce intestinal adhesions.Forty male Sprague-Dawley rats were divided into 4 groups: group A(gauze group),group B(hemostatic clamp group),group C(pincer group),group D(razor blade group),10 rats in each group. Animals were fed for 7 days before killed.The extent of adhesion was evaluated by Phillips scale and analyzed statistically. Results: The extents of adhesion in group A and B were grade Ⅰ by Phillips scale,grade IV in group C,grade Ⅲ in group D.The extent of adhesion in group C was different significantly from group A,B,and D(P
