Treatment of advanced pancreatic carcinoma with hand-assisted laparoscopic cholecystojejunostomy and gastroenterostomy combined with ~(125)I seed implantation
- VernacularTitle:手助腹腔镜胆肠、胃肠内引流术联合~(125)I粒子置入术治疗晚期胰腺癌
- Author:
Yu WU
;
Mingfang QIN
- Publication Type:Journal Article
- Keywords:
Laparoscopy;
~(125)I seed;
Carcinoma of the pancreas
- From:
Chinese Journal of Minimally Invasive Surgery
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the feasibility and clinical effect of hand-assisted laparoscopic cholecystojejunostomy and gastroenterostomy combined with()~(125)I seed implantation for the treatment of advanced pancreatic carcinoma.Methods Hand-assisted laparoscopic cholecystojejunostomy and gastroenterostomy combined with()~(125)I seed implantation was performed in 12 patients with advanced pancreatic carcinoma(pancreatic head,10 patients;pancreatic body,2 patients) between February 2002 and August 2004 in this hospital.Results All the operations were successfully accomplished.The operative time was 104~181 min(122?29 min),the operative blood loss was 45~152 ml(60?18 ml),and the length of hospital stay, 6~17 d(8.5?1.3 d).Postoperatively,the jaundice subsided gradually,and the patient's liver functions recovered to normal in 7~10 days.The abdominal pain disappeared in 3 patients and was obviously remitted in 7.Gastrointestinal dysfunction occurred in 2 patients and was cured with symptomatic therapy.Follow-up checkups with CT scannings in 10 patients for 6 months showed partial remission(PR) in 4 patients,no changes(NC) in 4 patients,and progressed disease(PD) in 2.Conclusions Hand-assisted laparoscopic internal drainage combined with()~(125)I seed implantation for the treatment of advanced pancreatic carcinoma is effective and micro-invasive.