Effects of ligustrazine on the endothelin-1-induced myocardial hypertrophy
- VernacularTitle:川芎嗪对内皮素引起心肌细胞肥大的影响
- Author:
Xiaoling ZHU
- Publication Type:Journal Article
- Keywords:
Endothelin-1;
Ligustrazine;
L-type calcium channel
- From:
Journal of Medical Postgraduates
2003;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the action of tetramethylpyrazines on cardiac myocyte hypertrophy induced by endothelin-1(ET-1). Methods: The blockers of L-type calcium channel(Larcidipine),TMPP and TMPH were used to influence protein synthesis stimulated by chronic ET-1. Results:(ET-1) group's intracellular protein content in cardiac myocyte was(279?39)?g/ml(17% higher than the control group,P
