In vitro Effect of Combined Traditional Chinese Medicine (Changqing Capsule) on The Tachyzoites of Toxoplasma gondii
- VernacularTitle:常青胶囊抗弓形虫速殖子实验研究
- Author:
Wei ZHANG
;
Furong FANG
;
Yuanjiao LIU
;
Liandi YANG
;
Ruoyu LUO
;
Fei GONG
;
Hui LU
;
Xiaoxia XU
- Publication Type:Journal Article
- Keywords:
Changqing capsule;
Toxoplasma gondii;
In vitro effect
- From:
Chinese Journal of Parasitology and Parasitic Diseases
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the in vitro effect of the traditional Chinese medicine on the tachyzoites of Toxoplasma gondii. Methods Supernatant (1^5 ml) of different doses of the traditional Chinese medicine (Changqing capsule) was collected by normal saline immersion and 2^5?10+4 Toxoplasma gondii tachyzoites were added in each paste well for 8 hours. Spiramycin, pyrimethamine and azithromycin in different doses were used as controls. Normal saline was used as negative control. Mice were inoculated with drug-treated tachyzoites intraperitoneally or intragastrically. The normal mice were subcultured after 8 days for 3 generations. Results The incident number of the infected mice was significantly different among groups with different drugs and doses: 2/60, 16/60, 10/60 and 10/60 in the groups of Changqing capsule, spiramycin, pyrimethamine and azithromycin respectively (P
