Antibiotics resistance profile and ERIC-PCR fingerprinting of Pseudomonas aeruginosa isolates resisting to imipenem
- VernacularTitle:耐亚胺培南绿脓假单胞菌的体外耐药监测与基因分型研究
- Author:
Shaohua PENG
;
Qin ZHU
;
Jian GU
;
Zhengjiang JIN
;
Congrong LI
- Publication Type:Journal Article
- Keywords:
Imipenem;
Pseudomonas aeruginosa;
Antibiotic resistance;
Genotyping
- From:
Chinese Journal of Laboratory Medicine
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore antibiotics resistance profiles and DNA fingerprints of Pseudomonas aeruginosa isolates resistant to imipenem (IRPA). Methods DNA fingerprints of 56 strains isolated from ICU (intensive care unit) were constructed by ERIC-PCR (enterobacter repetitive intergenic consensus-PCR). MICs (minimal inhibitory concentrations) were determined by agar dilution method.Results 33 genotypes were got from 56 strains by ERIC-PCR. Of 8 frequently used antibiotics, 5 of them showed resistance rate higher than 50%. Conclusion It is high time to pay attention to multi-drug resistance of IRPA. The exist of prevalence of IRPA clone in ICU advise us to control of IRPA in hospital effectively.
