Multidetector Computed Tomography for the Evaluation of Coronary Artery Disease; The Diagnostic Accuracy in Calcified Coronary Arteries, Comparing with IVUS Imaging.
10.3349/ymj.2014.55.3.599
- Author:
Jong Kwan PARK
1
;
Jong Youn KIM
;
Hyuck Moon KWON
;
Tae Hoon KIM
;
Seung Jin OH
;
Bum Kee HONG
;
Young Won YOON
;
Pil Ki MIN
;
Sung Woo KWON
;
Byoung Kwon LEE
Author Information
1. Division of Cardiology, Department of Internal Medicine, NHIS Ilsan Hospital, Goyang, Korea.
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Coronary artery disease;
coronary calcium score;
computed tomography;
intravascular ultrasound
- MeSH:
Aged;
Coronary Artery Disease/*diagnosis/*radiography/ultrasonography;
Female;
Humans;
Male;
Middle Aged;
Multidetector Computed Tomography/*methods;
Predictive Value of Tests;
Ultrasonography, Interventional/*methods
- From:Yonsei Medical Journal
2014;55(3):599-605
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Contrast enhanced multidetector computed tomography (MDCT) has been used as an alternative to coronary angiography for the assessment of coronary artery disease in the patient of the intermediate risk group. However, coronary calcium is a known limiting factor for MDCT evaluation. We investigated the diagnostic accuracy of 64-channel MDCT with each coronary artery calcium score (CACS) by compared with intravascular ultrasound (IVUS) imaging. MATERIALS AND METHODS: A total of 54 symptomatic patients with intermediate-risk (10 females, mean age 59.9+/-6.9 years, Framingham point scores 9-20) with 162 sites who had a culprit lesion on 64-channel MDCT before performing coronary angiography with IVUS were enrolled. Patients were divided into 4 subgroups depending on CACS: 0, 1-99, 100-399, and >400. Lesion length, external elastic membrane (EEM) cross sectional area (CSA), minimal luminal area, and plaque area were measured and compared between IVUS and MDCT. RESULTS: The correlation coefficients for the measurements of the EEM CSA, lumen CSA, and plaque area were r=0.514, r=0.837, and r=0.578, respectively. Furthermore, there were close correlation of plaque area between four subgroups of CACS (r=0.671, r=0.623, r=0.562, r=0.571, respectively). CONCLUSION: Despite the increase in CACS, the geometric analysis of coronary arteries using with 64-channel MDCT was comparable with IVUS in symptomatic patient of the intermediate risk group.
