The abnormality and genetic disorders of X chromosome involved in premature ovarian failure
- VernacularTitle:X染色体异常及其基因缺陷在卵巢早衰发病机制中的研究
- Author:
Xing WU
;
Yali HU
- Publication Type:Journal Article
- Keywords:
Premature ovarian failure;
The X chromosome;
Etiology
- From:
Journal of Medical Postgraduates
2004;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The premature ovarian failure(POF) may be inherited as an X-linked condition.Among genetic causes,X monosomy or X deletions and translocations are known to be responsible for POF.The X chromosome disorders such as mutations of the human bone morphogenetic protein-15 gene,the zinc finger protein gene,the X-inactivation-specific transcript gene,the drosophila melanogaster diaphanous gene,the X 2 linked aminopeptidaseP enzyme gene,the fragile X mental retardation gene are associated with POF.
