Neonate Septicemia Caused by Meticillin-resistant Coagulase Negative Staphylococcus in Children Hospital
- VernacularTitle:凝固酶阴性葡萄球菌致新生儿败血症的病原学及体外耐药监测
- Author:
Hongbing HU
;
Laorong YANG
;
Wei XIA
;
Dejuan LUO
;
Qiong CHEN
;
Ling LIU
- Publication Type:Journal Article
- Keywords:
Blood culture;
Neonate;
Septicemia;
CNS;
Drug resistance
- From:
Chinese Journal of Nosocomiology
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study the distribution and drug resistance of meticillin-resistante coagulase negative Staphylococcus(MRCNS) in neonate septicemia for rational use of antibiotics in clinic. METHODS The MRCNS isolates were detected by BD120 and ATB.Susceptibility test to 12 antibiotics was performed through disk diffusion test. RESULTS Totally 262 strains coagulase negative Staphylococcus(CNS) was isolated from 344 S.aureus strains.Among 262 CNS,there were 130 S.epidermidis strains(49.6%),94 S.hemolyticus strains(35.9%),21 S.hominis(8.01%),and 17 other kinds of Staphyloccus strains(6.49%).The isolated ratio of MRCNS was 65.0%(170/262).Susceptibility test showed that the MRCNS were multiple resistant. CONCLUSIONS CNS occupys the first place in infection of neonatal blood.The isolated ratio of MRCNS is high and shows multi-drug resistance.Vancomycin and some other glycopeptide antibiotics are the first choice for MRCNS infections.
