Significance of measurement of the expression CD28 on tumor infiltrating lymphocytes in patients with stomach cancer
- VernacularTitle:胃癌患者肿瘤浸润淋巴细胞CD28表达的检测及临床意义
- Author:
Huijun WANG
;
Xiaoguang LIU
;
Xiuguo JIN
;
Bo LIU
;
Guoan FANG
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Lymphocytes,tumor infiltrating;
Antigens, CD28
- From:
Chinese Journal of Laboratory Medicine
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the significance of measurement of the expression CD28 on tumor infiltrating lymphocytes in patients with stomach cancer.Methods Subjects for this investigation include the tumor tissues and its nearby normal tissues from 48 patients with stomach cancer.The levels of the expression of CD28, CD8 on tumor infiltrating lymphocytes were analyzed by flow cytometry.Results First, the levels of the expression of CD8+CD28+ and CD8-CD28+ on tumor infiltrating lymphocytes from the tumor tissues were remarkably lower than from its nearby normal tissues (P
