The protection role and parameter analysis of seed oil of hippophae rhamnoides L.on experimental hepatocirrhosis in mice
- VernacularTitle:沙棘籽油对小鼠实验性肝硬化的保护作用及参数分析
- Author:
Yan SHI
- Publication Type:Journal Article
- Keywords:
Seed oil of hippophae rhamnoides L.;
Glutamio pyruvic transaminase;
Superoxide dismutase;
Malondiadehyde;
Does-effect curve
- From:
Journal of Medical Postgraduates
2004;0(01):-
- CountryChina
- Language:Chinese
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Abstract:
Objective: To study the effect of seed oil of Hippophae rhamnoides L.(SOHR) on experimental hepatocirrhosis in mice. Methods: CCl_(4) was used in the experiment to form the model of experimental hepatocirrhosis in mice.In order to measure the possible changes of GPT and SOD in serum and SOD and MDA in tissues,we fed these mice with different concentration of SOHR for 45 days.The Does-Effect Curve was set up based on the data of this experiment. Results: SOHR could control the increase of GPT in serum and the decrease of SOD evidently,as well as the increase of MDA in tissues.The relationship of that the Hippophae rhamnoides dose with the decrease of GPT is significant. Conclusion: SOHR protects the experimental hepatacirrhosis in mice.
