The application of ThinPrep cytology in the diagnosis of superficial tumors
- VernacularTitle:液基细胞学在体表肿瘤诊断中的应用
- Author:
Hongai JI
;
Jinghua WANG
;
Xiaojun ZHOU
;
Yun JI
;
Hongjuan LIU
;
Weilin WU
;
Zhengmao QI
- Publication Type:Journal Article
- Keywords:
ThinPrep cytological test;
Tumor;
Fine needle aspiration;
Immunocytochemistry
- From:
Journal of Medical Postgraduates
2004;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the advantage of ThinPrep cytological test in tumor diagnosis by fine needle aspiration cytology. Methods: Using fine needle aspiration for smears,some of smears were made in conventional smears,the remains aspirating needles were washed with a transport washing solution.ThinPrep slides were made using the ThinPrep Processor. Results: In 84 cases FNA samples,49 cases were breast,29 cases were lymph node and 6 cases were others.Comparing with conventionally prepared specimens,ThinPrep processed samples showed the advantage in sensitivity or specificity.The lack of cellular debris,blood and exudates improve the ability to detect cellular abnormalities and speed up the time required for screening in ThinPrep processed samples.Rapid cell transfer from the sampling device to the transporing fluid containing the fixative ensure preservation of cell details with minimal artifactual changes. Conclusion: The use of Thinprep and by combination of FNAC and immunocytochemistry cytopathological diagnosis can be improved significantly.
