Studies on relationship between resistance to vancomycin and the coagulase activity of S.aureus
- VernacularTitle:金黄色葡萄球菌万古霉素耐药与凝固酶活性
- Author:
Hong DAI
;
Xuegong FAN
- Publication Type:Journal Article
- Keywords:
vancomycin;
drug resistibility;
coagulase
- From:
Chinese Journal of Clinical Laboratory Science
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes of coagulase activity and the DNA expression of coagulase of S.aureus during inducing vancomycin-resistant S.aureus in vitro.Methods Coagulase activity and DNA expression of coagulase of S.aureus were detected.Results The coagulase activity in 6 strains and the expression of coagulase DNA in 1 strain reduced.Conclusion Decreased coagulase activity and DNA expression are probably linked to vancomycin resistance of S.aureus.
