Relationship Between Hepatitis B Virus DNA Level in Saliva and Periodontal Status in Chronic Hepatitis B Patients
- VernacularTitle:慢性乙型肝炎患者唾液中HBV DNA水平与牙周状况的关系
- Author:
Rongsen LIU
;
Yabin LI
;
Haibin WANG
- Publication Type:Journal Article
- Keywords:
Chronic hepatitis B;
HBV DNA;
Saliva;
Real-time polymerase chain reaction(PCR);
Periodontum
- From:
Chinese Journal of Nosocomiology
1994;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To quantify the HBV DNA in saliva of chronic hepatitis B(CHB) patients and to study its relation to the periodontal status of the patients. METHODS HBV DNA were isolated from 60 patients with CHB by Trizol-chloroform method.HBV DNA levels were tested by real-time PCR technique and their relationship with plaque index,gingival index and probing depth was analyzed. RESULTS The positive rate of HBV DNA was (56.7%,) and the level of HBV DNA was 4.16+0.57(LogE,copies/ml) in saliva.The detectability of HBV DNA in saliva had no significant correlation with the values of oral clinical parameters. CONCLUSIONS The detectability and level of HBV DNA in saliva have no correlation with the oral hygienic parameters.Other sources of the HBV DNA may exist besides the serum in saliva.
