Antibiotic Combined Therapy as an Empirical Treatment for Febrile Patients with Neutropenia
- VernacularTitle:联合应用抗生素对中性粒细胞减少期感染的经验性治疗
- Author:
Lianning DUAN
;
Shuquan JI
;
Jingui CAO
;
Huiren CHEN
;
Hengxiang WANG
;
Hongmin YAN
;
Mei XUE
;
Jing LIU
- Publication Type:Journal Article
- Keywords:
Empirical treatment;
Neutropenia;
Fever
- From:
Chinese Journal of Nosocomiology
1994;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To assess the clinical effectiveness of antibiotic combined therapy for febrile neutropenia as an empirical treatment.METHODS We analyzed bacterial epidemiology form Jan 2001 to Feb 2003 and performed a study in 202 neutropenic febrile patients after chemotherapy or(HSCT).Three groups were divided.In first group(84 cases) carbapenems and vancomycin were used.In second group(78 cases)and in third group(40(cases)) used cephalosporin or quinolone.RESULTS Carbapenems plus vancomycin were with response rate of 93%,and(without) vancomycin were only 66%.Cephalosporin or quinolone was with response rate only of 30%.(CONCLUSIONS) Strong antibiotic with vancomycin is effective for treating patients with neutropenia and fever(under) limited bacterial epidemiology.
