Extended Spectrum ?-Lactamases Producing Enterobacter cloacae:Its Clinical Distribution and Drug Resistance
- VernacularTitle:产ESBLs阴沟肠杆菌的临床分布及耐药性研究
- Author:
Liangrong SHAO
;
Guozheng WANG
;
Mingzhong SUN
;
Huixiang JU
- Publication Type:Journal Article
- Keywords:
Enterobacter cloacae;
Extended-spectrum ?-lactamases;
Nosocomial infection;
Drug resistance
- From:
Chinese Journal of Nosocomiology
1994;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To explore the clinical distribution and drug resistance of extended-spectrum ?-lactamases(ESBLs) producing Enterobacter cloacae.METHODS The clinical distribution and drug resistance of 73 strains of E.cloacae and ESBLs producing E.cloacae identified in our hospital from Jan 2002 to Jan 2004 were analyzed.RESULTS Among them,the highest detectable rate was in respiratory department and from phlegm specimen.No ESBLs producing E.cloacae and non-(ESBLs) were resistant to imipenem;no non-ESBLs were resistant to cefepime,but some ESBLs producing E.cloacae was resistant to it;all ESBLs producing E.cloacae and non-(ESBLs) were resistant to ceftriaxone and amoxicillin/clavulanic acid.CONCLUSIONS E.cloacae is one of the(commonest) pathogens in nosocomial infection,and ESBLs producing E.cloacae has a high detectable rate,its drug resistance has increased;the clinic should choose antimicrobial agents rationally according to drug sensitive tests in vitro.
