An experimental study of the influence of impact to lamina on spinal cord blood flow
- VernacularTitle:椎板外冲击对脊髓血流影响的实验研究
- Author:
Haichun LIU
;
Yunzhen CHEN
;
Jianfeng ZHANG
- Publication Type:Journal Article
- Keywords:
Impact;
Spinal cord blood flow;
Spinal cord injury;
SD rats
- From:
Chinese Journal of Orthopaedic Trauma
2002;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the influences of impact of different loads to lamina on spinal cord with a closed spinal cord injury model and to explore the mechanisms of blood vessels in spinal cord injury. Methods 120 normal male SD rats were randomized into 4 groups, with 30 in each. Group A served as the control group which received no impact. In Groups B, C and D,impacts of 10, 15 and 20 N were given to lamina respectively. The blood flow in the spinal cord central gray matter and the dorsal white matter, the blood pressure and the heart rate were observed at different experimental time points. Results No obvious change was observed in the blood pressure and heart rate in every group at different time points. The spinal cord blood flow (SCBF) in Groups C and D varied in a regular pattern. Conclusions The impact load to lamina can affect the spinal cord mainly by altering the spinal cord microcirculation. The influence is the most obvious on the blood flow of microcirculation of the gray matter.
