Relationship between clinical feature and serum Titin antibodies in patients with myasthenia gravis
- VernacularTitle:重症肌无力患者血清连接素抗体与临床的关系
- Author:
Zhihui YAN
;
Dong XU
;
Fanying LIU
- Publication Type:Journal Article
- Keywords:
myasthenia gravis;
Titin-Ab;
thymoma
- From:
Journal of Clinical Neurology
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between level of Titin antibodies (Titin-Ab) and patient's condition and different thymic pathological patterns in patients with myasthenia gravis (MG), and to assess its value in the diagnosis and prognosis of MG.Methods The levels of Titin-Ab in serum from 52 patients with MG (MG group), 18 cases with other neurologic diseases (NMG group) and 50 normal controls (NC group) were detected using enzyme-linked immunosorbentassay (ELISA). 10 cases with MG who received operation on thymus were tested again after therapy.Results The positive rate of Titin-Ab in MG group was 36.5%,but not present in MNG and NC groups.The MG group!was significantly higher than those in NMG group and NC group (all P
