The study of CD4~+ CD8~+、CD4~+ CD25~+ regulative T cells in peripheral blood of patients with primary biliary cirrhosis and its association with the hepatic damnification
- VernacularTitle:原发性胆汁性肝硬化患者调节性T细胞及其与肝功能损伤的研究
- Author:
Yongzhe LI
;
Chaojun HU
;
Dinghua LIU
;
Dawei TONG
;
Shulan ZHANG
- Publication Type:Journal Article
- Keywords:
Liver Cirrhosis, Biliary;
CD4-Positive T-lymphocytes;
CD8-Positive T-lymphocytes;
Hemic and immune systems
- From:
Chinese Journal of Laboratory Medicine
2003;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To investigate the ratios of peripheral blood CD4+CD8+ and CD4+CD25+ regulative T cells, and explore the association with hepatic damnification and anti-AMA-M2 antibodies.Methods The percentage of CD4+CD8+T cells and CD4+CD25+T cells in peripheral blood from patients with primary biliary cirrhosis(PBC) (n=27)、26 patients with other hepatic desease、30 normal individuals were measured by flowcytometry.Results Patients with PBC had statistically higher levels of CD4+CD25+T cells than the patients with other hepatic disease (P
