Influence of valsartan and amlodipine on the left ventricular diastolic function,endothelium function and serum insuline level in aged hyperpietic patients
- VernacularTitle:缬沙坦和氨氯地平对老年原发性高血压病患者左心室和血管内皮舒张功能及胰岛素水平的影响
- Author:
Pei HUANG
;
Ximing LI
;
Ronglin ZHANG
- Publication Type:Journal Article
- Keywords:
Hypertension;
Primary;
Valsartan;
Amlodipine;
Left ventricular diastolic function;
Endothelium function;
Insuline
- From:
Journal of Medical Postgraduates
2003;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the effect of valsartan and amlodipine on the reduction of blood pressure in aged hyperpietic patients,as well as on the improvement of left ventricular diastolic function,endothelium function and insuline resistence. Methods: We divided 40 cases of aged hypertension patients(1 to 2 grade) into Valsartan and Amlodipine groups at random,giving valsartan 80-160 mg or amlodipine 5-10 mg,respectively,for 12 weeks as a treating period.We measured the blood pressure twice a week,observed the differences of blood pressure and heart rate before and after the treatment,as well as the changes of insuline sensitivity,left ventricular diastolic function and endothelium vascular disatolic function. Results and Conclusion: Both valsartan and amlodipine can effectivly reduce the blood pressure of aged hypertension patients(l to 2 grade).They can also improve the diastolic function,insuline resistance and endothelium dependent vascular diastolic function.
