Expression of vascular endothelial growth factor in small cell carcinoma of uterus cervix and its clinical significance
- VernacularTitle:宫颈小细胞癌组织中血管内皮生长因子的表达及临床意义
- Author:
Zhi JIANG
;
Baorui LIU
;
Xiangshan FAN
- Publication Type:Journal Article
- Keywords:
Small cell carcinoma of cervis;
Vascular endothelial growth factor;
Immunohistochemistry
- From:
Journal of Medical Postgraduates
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the expression of vascular endothelial growth factor(VEGF) in small cell carcinoma of cervis(SCCC) and its relationship with the clinical and pathological features,so as to predict the metastasis of SCCC,to evaluate the prognosis and to manage a proper treatment. Methods: EnVision two step immunohistochemical method was used to observe the expession of VEGF in the samples of small cell carcinoma of cervis. Results: Four samples were obtained from surgical specimens of the patients with SCCC in our hospital.In all the samples,the expression of VEGF was positive. Conclusion: VEGF is closely related with the oncogenesis and development of SCCC.In the earlier period of SCCC,the lymph node involvement and vascular invasion are common.The aggressive progression of SCCC must have something to do with the highly expression of VEGF.The expression of VEGF can be used as an index in selecting treatment and predicting prognosis of SCCC.
