Screening of the tumor cytotoxic activity of sixteen species of mangrove plants in Hainan
- VernacularTitle:海南16种红树植物的肿瘤细胞毒活性筛选
- Author:
Haofu DAI
- Publication Type:Journal Article
- Keywords:
mangrove plants;
tumor cytotoxic activity;
HeLa cells;
assay
- From:
Chinese Journal of Marine Drugs
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the growth inhibitory effect of the extracts from sixteen species of mangrove plants in Hainan on HeLa cells. Methods Sixteen species of mangrove plants were collected in Wenchang county,Hainan province,and were extracted with ethanol.The ethanol extracts were dissolved in water,partitioned by ethyl acetate,and ethyl acetate and water extract were obtained.Growth inhibitory rates of the extracts on HeLa cells were determined by MTT assay.Results The ethyl acetate extracts from six species of mangrove plants showed growth inhibitory activity on HeLa cells,and the extracts from Acrostichum aureurm and Heritiera littoralis showed strong activity,the IC_(50) values of which were 6.3,9.5 ?g mL~(-1),respectively.Conclusion The ethyl acetate extracts from six species of mangrove plants showed growth inhibitory effects on HeLa cells,whereas the water extracts did not.
