Effects of intensive insulin therapy on the intestinal permeability in sepsis patients
- VernacularTitle:强化胰岛素治疗对脓毒症病人肠黏膜通透性的影响
- Author:
Bin SHI
;
Hong GUO
;
Bin ZHANG
;
Chao YIN
;
Qiliang HOU
;
Yongqiang CAO
;
Xinzhong WEN
- Publication Type:Journal Article
- Keywords:
Insulin;
Sepsis;
D-lactic acid;
Diamine oxidase
- From:Parenteral & Enteral Nutrition
2010;17(1):11-12,16
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To discuss the effect of intensive insulin therapy on D-lactic acid and diamine oxidase level in patients with sepsis.Methods: 48 patients was divided into control group and conventional group randomly.Content of D-lactic acid and diamine oxidase in serum was detected with absorption spectrometry before and after therapy.Result: D-lactic acid and diamine oxidase in patients decreased significantly in control group compared to that of conventional group.Conclusion: Insulin can depress interstinal permeability and ameliorate sepsis symptom resulted from bacterial translocation from intestine.
