Study of vitro thrombolytic test to the consumptions of urokinase in thrombolytic therapy of acute cerebral infarction
- VernacularTitle:体外溶栓试验确定急性脑梗死治疗中尿激酶用量的研究
- Author:
Hongliang DENG
;
Xiaodong YUAN
;
Guangzeng WANG
- Publication Type:Journal Article
- Keywords:
urokinase;
cerebral infarction;
vitro thrombolytic test;
thrombolytic therapy
- From:
Journal of Clinical Neurology
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of vitro thrombolytic test on the consumptions of urokinase(UK) in thrombolytic therapy of acute cerebral infarction.Methods The patients of acute cerebral infarction were treated with UK at the dose determined by vitro thrombolytic test,and then were given UK 40MU each day in the later 7 days.The degree of neurologic impairment,fibrinogen(Fbg) level,polyreaction speed(FMPV) and maximum luminosity(ODmax) were examined at different time point.Results Thrombolytic therapy could significantly reduce neurologic impairment as compared with control group((P