Effects of classical intrafascial supracervical hysterectomy on immune functions-A randomized controlled trial
- VernacularTitle:腹腔镜筋膜内子宫切除术对机体免疫功能影响的随机对照研究
- Author:
Qian ZHAO
;
Aiping BIAN
;
Quanling FENG
- Publication Type:Journal Article
- Keywords:
Laparoscopy;
Hysterectomy;
Immune function;
T-lymphocyte;
Cytokine
- From:
Chinese Journal of Minimally Invasive Surgery
2005;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study effects of classical intrafascial supracervical hysterectomy(CISH) on immune functions.Methods A total of 60 women with benign gynecopathy requiring a hysterectomy were randomly divided into two groups with 30 patients in each group,receiving either CISH or abdominal hysterectomy(AH).The white blood cell(WBC) count and neutrophil granulocyte percentage before and 1 day after the surgery,and peripheral T-lymphocyte subgroup(CD_3,CD_4,and CD_8),(interleukin-2)(IL-2),and interleukin-10(IL-10) 1 day before and 1 and 4 days after the surgery were measured,respectively. Results Postoperative levels of CD_3 and CD_4 in both groups decreased significantly at 1 day after operation(CISH Group: q_(CD3)=6.033,(q_CD4=4.763);AH Group: q_(CD3)=11.043,q_(CD4)=9.202;P0.05),and were significantly higher(q_(CD3)=6.531,q_(CD4)=5.269,P0.05) in the CISH Group.The IL-2 levels were significantly lower at 1 and 4 days after operation than before the operation in the AH Group((q_(1-2)=11.187),q_(1-3)=5.404,P
