Prevention and treatment of chemotherapy-induced intestinal barrier dysfunction
- VernacularTitle:化疗对肠屏障功能的影响及其防治
- Author:
Yousheng LI
;
Jieshou LI
- Publication Type:Journal Article
- Keywords:
Chemotherapy;
Intestinal barrier;
Therapy
- From:
Journal of Medical Postgraduates
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Chemotherapy has been shown to be effective in the treatment of patients malignancies, however, anticancer drugs, particularly high-dose, also damage other chemosensitive tissues such as the intestinal mucosa, and these adverse effects can impair intestinal mucosal barrier. The derangement in the barrier function plays a central role in the pathophysiology of systemic infection, shock, and sepsis syndrome. The chemotherapy-induced intestinal barrier dysfunction and its prevention and treatment had been reviewed.