The clinical significance of S/CO qualitative determination of hepatitis B surface antibody
10.3760/cma.j.issn.1673-4130.2009.01.006
- VernacularTitle:乙型肝炎病毒表面抗体定性测定S/CO的临床意义
- Author:
Penghui SHI
;
Yongqin LI
;
Kunjing GENG
- Publication Type:Journal Article
- Keywords:
Hepatitis B antibodies;
Enzyme-linked immunosorbent assay;
Samples;
Qualitative research
- From:
International Journal of Laboratory Medicine
2009;30(1):14-15,19
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relativity of S/CO qualitative determination of hepatitis B surface antibody and quantitative assay.Methods The different concentrations of sera were determined with time-resolved fluorescence immunoassay and enzyme-linked immunosorbent assay. The standard curve was drawn and the equation was established.Results In the curve, S/CO level was positively correlative to the quantitative detection value, and the conversion equation was Y=8.911 8×e0.177 4X.The intraclass correlation coefficient of S/CO calculating level and quantitative value was 0.934.Conclusion The content of hepatitis B surface antibody can be estimated by S/CO value. It can be used in basic-level laboratories which don′t undertake the quantitative determination of HBV markers.