Study on the bio-safety of a multifunctional dressing based on isobutyl-chitosan
- VernacularTitle:异丁基壳聚糖多功能敷料的生物安全性
- Author:
Liangming LIU
;
Kunlun TINA
;
Xiaoqing FAN
;
Zifu LIAO
;
Youfang DIAO
;
Nan XIAO
;
Donghong LI
- Publication Type:Journal Article
- Keywords:
wound dressing;
isobutyl-chitosan;
sensitization;
irritation;
systemic acute toxi-city
- From:
Chinese Journal of Marine Drugs
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the bio-safety of a multifunctional dressing based on isobutyl-chitosan,a derivative of chitosan.Methods To investigate the local irritation of the multifunctional dressing by skin,subcutaneous and eye application,determine its sensitization by patch test and observe its systemic acute toxicity by abdominal injection.Results The isobutyl-chitosan multifunctional dressing had no irritation,sensitization and systemic acute toxicity.Conclusion The isobutyl-chitosan multifunctional dressing has a good bio-safety as a wound dressing.
