Clinical study of treating systemic lupus erythematosus encephalopathy with different immuno-suppressants
- VernacularTitle:不同免疫抑制剂治疗狼疮性脑病的临床研究
- Author:
Linping LIANG
;
Lei WANG
- Publication Type:Journal Article
- Keywords:
systemic lupus erythematosus;
Methyllprednisolone;
CTX;
IFO
- From:
Journal of Clinical Neurology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy and safety of three kinds of immunosuppressant on systemic lupus erythematosus encephalopathy. Methods 44 cases with systemic lupus erythematosus encephalopathy were randomly assigned to receive high dose of Methyllprednisolone, Cytoxan (CTX) or Ifosfamide (IFO). The levels of ESR and serum C_3 were detected at different time after treatments. The effect and safety of these treatments were evaluated. Results (1) After treatment, the levels of ESR decreased significantly ((P)0.05). More decrease of ESR was found in CTX group and IFO group than in Methyllprednisolone group (all (P