Sensitivity of radiotherapy on the cells in midsection and edge of glioma
- VernacularTitle:胶质瘤中心部位及瘤周细胞对放疗的敏感性
- Author:
Xiang LIU
;
Rufei DAI
;
Hongyi LIU
- Publication Type:Journal Article
- Keywords:
glioma;
X-ray;
radiotherapy
- From:
Journal of Clinical Neurology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the sensitivity of radiotherapy on the cells in midsection and edge of glioma. Methods The glioma models were established in SD rats and exposed to X radiation. Proliferating cell nuclear antigen (PCNA), apoptosis rate and cell phase of the cells in the midsection and edge of glioma were detected by immunohistochemical assay, terminal transferase dUTP nick ending labeling (TUNEL) and flow cytometry. Results Immunohistochemical assay showed that PCNA-LI of the edge cells was significantly lower than that of midsection cells ((P
