The new treatment target of diabetes: islet β-cell mass
10.3760/cma.j.issn.1000-6699.2009.03.042
- VernacularTitle:糖尿病治疗的新靶点:胰岛β细胞量
- Author:
Lingqing YUAN
;
Eryuan LIAO
- Publication Type:Journal Article
- Keywords:
Islet β-cell mass;
Diabetes mellitus;
Apoptosis
- From:
Chinese Journal of Endocrinology and Metabolism
2009;25(3):-
- CountryChina
- Language:Chinese
-
Abstract:
Pancreatic islet β-cell mass is regulated by β-cell replication, nengenesis, apnptosis and cell size. β-cetl mass in diahetic patients is conspicuously less than that in normal subjects. Induction of β-cell regeneration and inhibition of β-cell apoptosis is the new target of diabetes treatment.