The progress of granulocyte-macrophage colony-stimulating factor on the mechanism of acute lung injury
- VernacularTitle:粒细胞-巨噬细胞集落刺激因子在急性肺损伤发病机制中的研究进展
- Author:
Qian WANG
;
Yong SONG
- Publication Type:Journal Article
- Keywords:
Granulocyte-macrophage colong stimulating factor;
Acute lung injury;
Apoptosis
- From:
Journal of Medical Postgraduates
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Acute lung injury is the result of organism autodestruction due to the mediators of inflammation overexpress. Recent studies suggest that GM-CSF correlate with alveolar macrophage function, lung host defense reaction and pulmonary surfactant homeostasis. GM-CSF influences regulation and signal transduction pathway of inflammation and apoptosis. These research progresses was been reviewed.