Evaluation of HBV drug-resistance in vitro and the molecular mechanism of resistance to nucleoside analogue therapy
- VernacularTitle:核苷类抗乙型肝炎病毒药物耐药的分子机制与体外评价
- Author:
Yan ZHANG
;
Xuefan BAI
- Publication Type:Journal Article
- Keywords:
Hepatitis B virus;
Nucleoside analogues;
Molecular mechanism of drug-resistance
- From:
Journal of Medical Postgraduates
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Nucleoside analogues are currently the main drug therapy against HBV infection. However, this type of therapy can cause gene mutations in HBV that result in drug resistance. The types of mutations caused by nucleoside analogues and the molecular mechanism of in vitro drug-resistance were reveiwed.
