Natural nitrogenous compounds from the South China Sea marine sponge Clathria fasciculate
- VernacularTitle:南海小束格海绵中的天然含氮化合物
- Author:
Shumei ZHOU
- Publication Type:Journal Article
- Keywords:
sponge;
nitrogenous compounds;
riboside;
structure identification
- From:
Chinese Journal of Marine Drugs
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the bioactive chemical constituents of the marine sponge Clathria fasciculate which collected from the South China Sea.Methods Using organic solvent for crude extraction and column chromatography for further isolation. Chemical structures were identified on the basis of spectrum data of ~(1)H-NMR, ~(13)C-NMR, IR, UV and MS. The stereochemistry was determined by comparing optical rotation values with authentic data. Results and Conclusion Six nitrogenous organic compounds were elucidated as adenosine(Ⅰ), uridine(Ⅱ), thymidine(Ⅲ), hypoxanthine(Ⅳ), thymine(Ⅴ) and uracil(Ⅵ) which were obtained from the (n-butanol) extract.
