Comparison of postoperative hepatic functions between laparoscopic and open colorectal surgery
- VernacularTitle:腹腔镜和开腹结直肠癌手术术后肝功能的比较
- Author:
Ying WANG
;
Kai PAN
;
Dong WANG
- Publication Type:Journal Article
- Keywords:
Liver function;
Pneumoperitoneum;
Colorectal cancer;
Laparoscopy
- From:
Chinese Journal of Minimally Invasive Surgery
2005;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the difference on postoperative hepatic functions between laparoscopic and conventional surgery for colorectal cancers. Methods In this prospective study, a laparoscopic group ( n =20) was compared with an open group ( n =20). Blood samples were obtained at 1, 24, 48, and 72 hours postoperation respectively to perform liver function tests, including total bilirubin (TBil), albumin (Alb), gamma-glutamyl transpeptidase (?-GT), alkaline phosphatase (ALP), aspartate aminotransferase (AST) and alanine aminotransferase (ALT). Results Of the both groups, serum Alb and ALP levels decreased, and TBil and GGT levels remained unchanged. Postoperative ALT and AST levels transiently increased by threefold and returned to near baseline levels at 72 hours. There was no postoperative liver failure or mortality in both groups. Conclusions Laparoscopic colorectal surgery results in postoperative elevation of hepatic transaminases but does not adversely alter hepatic functions to any greater extent than open colorectal surgery.
